diff --git a/CHANGELOG.md b/CHANGELOG.md
index d316e84d3..b3a3cf675 100644
--- a/CHANGELOG.md
+++ b/CHANGELOG.md
@@ -1,5 +1,24 @@
 # Changelog
 
+## 2.46.0-rc.0 / 2023-07-20
+
+* [FEATURE] Promtool: Add PromQL format and label matcher set/delete commands to promtool. #11411
+* [FEATURE] Promtool: Add push metrics command. #12299
+* [ENHANCEMENT] Promtool: Read from stdin if no filenames are provided in check rules. #12225
+* [ENHANCEMENT] Hetzner SD: Support larger ID's that will be used by Hetzner in September. #12569
+* [ENHANCEMENT] Kubernetes SD: Add more labels for endpointslice and endpoints role. #10914
+* [ENHANCEMENT] Kubernetes SD: Do not add pods to target group if the PodIP status is not set. #11642
+* [ENHANCEMENT] OpenStack SD: Include instance image ID in labels. #12502
+* [ENHANCEMENT] Remote Write receiver: Validate the metric names and labels. #11688
+* [ENHANCEMENT] Web: Initialize `prometheus_http_requests_total` metrics with `code` label set to `200`. #12472
+* [ENHANCEMENT] TSDB: Add Zstandard compression option for wlog. #11666
+* [ENHANCEMENT] TSDB: Support native histograms in snapshot on shutdown. #12258
+* [BUGFIX] Histograms: Fix parsing of float histograms without zero bucket. #12577
+* [BUGFIX] Histograms: Fix scraping native and classic histograms missing some histograms. #12554
+* [BUGFIX] Histograms: Enable ingestion of multiple exemplars per sample. 12557
+* [BUGFIX] File SD: Fix path handling in File-SD watcher to allow directory monitoring on Windows. #12488
+* [BUGFIX] Linode SD: Cast `InstanceSpec` values to `int64` to avoid overflows on 386 architecture. #12568
+* [BUGFIX] TSDB: Handle TOC parsing failures. #10623
 
 ## 2.45.0 / 2023-06-23
 
diff --git a/VERSION b/VERSION
index e599014ea..57ff064ad 100644
--- a/VERSION
+++ b/VERSION
@@ -1 +1 @@
-2.45.0
+2.46.0-rc.0
diff --git a/web/ui/module/codemirror-promql/package.json b/web/ui/module/codemirror-promql/package.json
index c7fafb133..c5f244fff 100644
--- a/web/ui/module/codemirror-promql/package.json
+++ b/web/ui/module/codemirror-promql/package.json
@@ -1,6 +1,6 @@
 {
   "name": "@prometheus-io/codemirror-promql",
-  "version": "0.45.0",
+  "version": "0.46.0-rc.0",
   "description": "a CodeMirror mode for the PromQL language",
   "types": "dist/esm/index.d.ts",
   "module": "dist/esm/index.js",
@@ -29,7 +29,7 @@
   },
   "homepage": "https://github.com/prometheus/prometheus/blob/main/web/ui/module/codemirror-promql/README.md",
   "dependencies": {
-    "@prometheus-io/lezer-promql": "0.45.0",
+    "@prometheus-io/lezer-promql": "0.46.0-rc.0",
     "lru-cache": "^6.0.0"
   },
   "devDependencies": {
diff --git a/web/ui/module/lezer-promql/package.json b/web/ui/module/lezer-promql/package.json
index 847a9610e..bc9878485 100644
--- a/web/ui/module/lezer-promql/package.json
+++ b/web/ui/module/lezer-promql/package.json
@@ -1,6 +1,6 @@
 {
   "name": "@prometheus-io/lezer-promql",
-  "version": "0.45.0",
+  "version": "0.46.0-rc.0",
   "description": "lezer-based PromQL grammar",
   "main": "dist/index.cjs",
   "type": "module",
diff --git a/web/ui/package-lock.json b/web/ui/package-lock.json
index ac365d0d0..dc961444b 100644
--- a/web/ui/package-lock.json
+++ b/web/ui/package-lock.json
@@ -28,10 +28,10 @@
     },
     "module/codemirror-promql": {
       "name": "@prometheus-io/codemirror-promql",
-      "version": "0.45.0",
+      "version": "0.46.0-rc.0",
       "license": "Apache-2.0",
       "dependencies": {
-        "@prometheus-io/lezer-promql": "0.45.0",
+        "@prometheus-io/lezer-promql": "0.46.0-rc.0",
         "lru-cache": "^6.0.0"
       },
       "devDependencies": {
@@ -61,7 +61,7 @@
     },
     "module/lezer-promql": {
       "name": "@prometheus-io/lezer-promql",
-      "version": "0.45.0",
+      "version": "0.46.0-rc.0",
       "license": "Apache-2.0",
       "devDependencies": {
         "@lezer/generator": "^1.2.3",
@@ -20765,7 +20765,7 @@
     },
     "react-app": {
       "name": "@prometheus-io/app",
-      "version": "0.45.0",
+      "version": "0.46.0-rc.0",
       "dependencies": {
         "@codemirror/autocomplete": "^6.7.1",
         "@codemirror/commands": "^6.2.4",
@@ -20783,7 +20783,7 @@
         "@lezer/lr": "^1.3.6",
         "@nexucis/fuzzy": "^0.4.1",
         "@nexucis/kvsearch": "^0.8.1",
-        "@prometheus-io/codemirror-promql": "0.45.0",
+        "@prometheus-io/codemirror-promql": "0.46.0-rc.0",
         "bootstrap": "^4.6.2",
         "css.escape": "^1.5.1",
         "downshift": "^7.6.0",
@@ -23423,7 +23423,7 @@
         "@lezer/lr": "^1.3.6",
         "@nexucis/fuzzy": "^0.4.1",
         "@nexucis/kvsearch": "^0.8.1",
-        "@prometheus-io/codemirror-promql": "0.45.0",
+        "@prometheus-io/codemirror-promql": "0.46.0-rc.0",
         "@testing-library/react-hooks": "^7.0.2",
         "@types/enzyme": "^3.10.13",
         "@types/flot": "0.0.32",
@@ -23487,7 +23487,7 @@
         "@lezer/common": "^1.0.3",
         "@lezer/highlight": "^1.1.6",
         "@lezer/lr": "^1.3.6",
-        "@prometheus-io/lezer-promql": "0.45.0",
+        "@prometheus-io/lezer-promql": "0.46.0-rc.0",
         "@types/lru-cache": "^5.1.1",
         "isomorphic-fetch": "^3.0.0",
         "lru-cache": "^6.0.0",
diff --git a/web/ui/react-app/package.json b/web/ui/react-app/package.json
index 81eba150a..54af5a234 100644
--- a/web/ui/react-app/package.json
+++ b/web/ui/react-app/package.json
@@ -1,6 +1,6 @@
 {
   "name": "@prometheus-io/app",
-  "version": "0.45.0",
+  "version": "0.46.0-rc.0",
   "private": true,
   "dependencies": {
     "@codemirror/autocomplete": "^6.7.1",
@@ -19,7 +19,7 @@
     "@lezer/common": "^1.0.3",
     "@nexucis/fuzzy": "^0.4.1",
     "@nexucis/kvsearch": "^0.8.1",
-    "@prometheus-io/codemirror-promql": "0.45.0",
+    "@prometheus-io/codemirror-promql": "0.46.0-rc.0",
     "bootstrap": "^4.6.2",
     "css.escape": "^1.5.1",
     "downshift": "^7.6.0",