diff --git a/CMakeLists.txt b/CMakeLists.txt
index 3e12047..6589ef1 100644
--- a/CMakeLists.txt
+++ b/CMakeLists.txt
@@ -10,24 +10,108 @@ set(default_build_heap_checker ON)
 set(default_build_debugalloc ON)
 set(default_build_minimal OFF)
 
-set(tcmalloc_default_alignment 16)
+set(default_tcmalloc_alignment 16)
 set(need_nanosleep ON)
 
-if(MINGW)
+set(host "${CMAKE_HOST_SYSTEM_NAME}")
+if(host MATCHES ".*-mingw.*")
     set(default_build_minimal ON)
     set(default_build_debugalloc OFF)
     set(need_nanosleep OFF)
-elseif(CYGWIN)
+elseif(host MATCHES ".*-cygwin.*")
     set(default_build_heap_checker OFF)
     set(default_build_cpu_profiler OFF)
-elseif(FREEBSD)
+elseif(host MATCHES ".*-freebsd.*")
     set(default_build_heap_checker OFF)
-elseif(DARWIN)
+elseif(host MATCHES ".*-darwin.*")
     set(default_build_heap_checker OFF)
 endif()
 
-option(gperftools_build_cpu_profiler "Build cpu-profiler" ${default_build_cpu_profiler})
-option(gperftools_build_heap_profiler "Build heap-profiler" ${default_build_heap_profiler})
-option(gperftools_build_heap_checker "Build heap-checker" ${default_build_heap_checker})
-option(gperftools_build_debugalloc "Build debugalloc" ${default_build_debugalloc})
-option(gperftools_build_minimal "Build fully minimal" ${default_build_minimal})
+include(CheckCSourceCompiles)
+include(CheckFunctionExists)
+include(CheckIncludeFile)
+include(CheckTypeSize)
+include(CMakeDependentOption)
+
+check_c_source_compiles("int main() { return __s390__; }" s390)
+if(s390)
+    set(default_enable_libunwind OFF)
+    set(default_enable_backtrace ON)
+else()
+    set(default_enable_libunwind ON)
+    set(default_enable_backtrace OFF)
+endif()
+
+check_c_source_compiles("int main() { return __PPC64__; }" PPC64)
+if(PPC64)
+    set(default_enable_libunwind OFF)
+    set(default_tcmalloc_pagesize 64)
+else()
+    set(default_enable_libunwind ON)
+    set(default_tcmalloc_pagesize 8)
+endif()
+
+option(
+    gperftools_build_minimal
+    "Build only tcmalloc-minimal (and maybe tcmalloc-minimal-debug)"
+    ${default_build_minimal})
+cmake_dependent_option(
+    gperftools_build_cpu_profiler "Build cpu-profiler" ${default_build_cpu_profiler}
+    "NOT gperftools_build_minimal" OFF)
+cmake_dependent_option(
+    gperftools_build_heap_profiler "Build heap-profiler" ${default_build_heap_profiler}
+    "NOT gperftools_build_minimal" OFF)
+cmake_dependent_option(
+    gperftools_build_heap_checker "Build heap-checker" ${default_build_heap_checker}
+    "NOT gperftools_build_minimal" OFF)
+cmake_dependent_option(
+    gperftools_build_debugalloc "Build debugalloc" ${default_build_debugalloc}
+    "NOT gperftools_build_minimal" OFF)
+
+option(gperftools_stacktrace_via_backtrace
+       "Enable use of backtrace() for stacktrace capturing (may deadlock)"
+       ${default_enable_backtrace})
+option(gperftools_enable_libunwind
+       "Enable libunwind linking"
+       ${default_enable_libunwind})
+
+set(gperftools_tcmalloc_pagesize ${default_tcmalloc_pagesize}
+    CACHE STRING "Set the tcmalloc internal page size")
+set_property(CACHE gperftools_tcmalloc_pagesize PROPERTY STRINGS "8" "32" "64")
+if(gperftools_tcmalloc_alignment NOT STREQUAL "8" AND
+   gperftools_tcmalloc_alignment NOT STREQUAL "32" AND
+   gperftools_tcmalloc_alignment NOT STREQUAL "64")
+    message(WARNING
+        "Invalid gperftools_tcmalloc_pagesize (${gperftools_tcmalloc_pagesize}),"
+        "setting to default value (${default_tcmalloc_pagesize})")
+    set(gperftools_tcmalloc_pagesize ${default_tcmalloc_pagesize})
+endif()
+
+set(gperftools_tcmalloc_alignment ${default_tcmalloc_alignment}
+    CACHE STRING "Set the tcmalloc allocation alignment")
+set_property(CACHE gperftools_tcmalloc_alignment PROPERTY STRINGS "8" "16")
+if(gperftools_tcmalloc_alignment NOT STREQUAL "8" AND
+   gperftools_tcmalloc_alignment NOT STREQUAL "16")
+    message(WARNING
+        "Invalid gperftools_tcmalloc_alignment (${gperftools_tcmalloc_alignment}), "
+        "setting to default value (${default_tcmalloc_alignment})")
+    set(gperftools_tcmalloc_alignment ${default_tcmalloc_alignment})
+endif()
+
+# TODO: `target_add_definitions` for above (i.e. `TCMALLOC_32K_PAGES`,
+#       `TCMALLOC_ALIGN_8BYTES`)
+
+# TODO: Find `objcopy` with `--weaken` support
+
+check_type_size("__int64" __INT64)
+set(CMAKE_EXTRA_INCLUDE_FILES "malloc.h")
+check_type_size("struct mallinfo" struct_mallinfo)
+set(CMAKE_EXTRA_INCLUDE_FILES "elf.h")
+check_type_size("Elf32_Versym")
+check_function_exists("sbrk" HAS_SBRK)
+check_function_exists("geteuid" HAS_GETEUID)
+check_function_exists("fork" HAS_FORK)
+check_include_file("features.h" HAS_FEATURES)
+check_include_file("malloc.h" HAS_MALLOC)
+check_include_file("glob.h" HAS_GLOB)
+check_include_file("execinfo.h" HAS_EXECINFO)