diff --git a/cmake/DefineTargetVariables.cmake b/cmake/DefineTargetVariables.cmake
index ada0152..38916c5 100644
--- a/cmake/DefineTargetVariables.cmake
+++ b/cmake/DefineTargetVariables.cmake
@@ -4,10 +4,17 @@ endif()
 
 macro(define_target_variables)
   check_cxx_source_compiles("int main() { return __i386__; }" i386)
-  check_cxx_source_compiles("int main() { return __s390__; }" s390)
-  check_cxx_source_compiles("int main() { return __PPC64__; }" PPC64)
   check_cxx_source_compiles("int main() { return __x86_64__; }" x86_64)
+  check_cxx_source_compiles("int main() { return __s390__; }" s390)
+if(APPLE)
+  check_cxx_source_compiles("int main() { return __arm64__; }" ARM)
+  check_cxx_source_compiles("int main() { return __ppc64__; }" PPC64)
+  check_cxx_source_compiles("int main() { return __ppc__; }" PPC)
+else()
   check_cxx_source_compiles("int main() { return __arm__; }" ARM)
+  check_cxx_source_compiles("int main() { return __PPC64__; }" PPC64)
+  check_cxx_source_compiles("int main() { return __PPC__; }" PPC)
+endif()
   check_cxx_source_compiles("int main() { return __FreeBSD__; }" FreeBSD)
   check_cxx_source_compiles("int main() { return __MINGW__; }" MINGW)
   check_cxx_source_compiles("int main() { return __linux; }" LINUX)